Anti-COMT Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K002727P-50ul	solarbio	50ul	960.00元
K002727P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-COMT Polyclonal Antibody
别名	HEL-S-98n
应用	WB IP
稀释比例	WB 1:500-2000. IP 1:50-100.
交叉反应	Human Mouse
蛋白分子量	30kDa
Gene ID	1312
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human COMT
性状	液体
Public Immunogen Range	Recombinant protein of human COMT
Subcellular Locations	Cell membrane Cytoplasm Extracellular side Single-pass type II membrane protein
Swiss Prot	P21964
克隆类型	Polyclonal Antibody
背景资料	Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.